Tīmeklis2024. gada 29. apr. · The involvement of lncRNA FEZF1-AS1 has been analyzed in many types of cancers, while its roles in non-small cell lung cancer (NSCLC) remains unclear. We then explored the role of FEZF1-AS1 in NSCLC. qPCR and western blot were performed to measure gene expression. FEZF1-AS1, miR-34a, and NOTCH-1 … Tīmeklis2024. gada 1. nov. · Increased FEZF1-AS1 expression promoted gastric cancer cell proliferation in vitro. Additionally, FEZF1-AS1 was upregulated in chemo-resistant GC tissues. The regulatory effect of FEZF1-AS1 on multi-drug resistance (MDR) in GC cells and the underlying mechanism was investigated.
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Tīmeklis2024. gada 2. sept. · FEZF1-AS1, FEZ family zinc finger 1 antisense RNA 1; shRNA, short hairpin RNA; NC, negative control; MMP, matrix metalloproteinase. miR-1236-3p is a direct target of FEZF1-AS lncRNAs contain binding sites that are complementary to miRNAs, which permits them to serve as miRNA ‘sponges’ ( 28, 29 ). Tīmeklis2024. gada 4. dec. · FEZF1-AS1 might be a key regulator of cell cycle, EMT and Wnt/beta-catenin signaling in NPC cells. Our findings suggested that dysregulation of FEZF1-AS1 contributed to the progression of lung adenocarcinoma (LAD), which might be a potential target for LAD therapy. arti dari ignore adalah
Frontiers LncRNA FEZF1-AS1 Promotes Multi-Drug Resistance …
Tīmeklis2024. gada 16. febr. · FEZF1-AS1 is an lncRNA producing a 2564 bp transcript, located in chromosome 7. In this study, we demonstrated that FEZF1-AS1 was overexpressed in the tumor tissues than the paracancerous tissues; furthermore, overexpression of FEZF1-AS1 was observed in larger tumors, advanced gastric cancer and predicted … TīmeklisFEZF1-AS1 expression levels were studied in cell lines and tissues of human ovarian cancer. In vitro studies were performed to evaluate the impact of FEZF1-AS1 knock-down on the proliferation, invasion, migration and apoptosis of OC cells. Interactions of FEZF1-AS1 and its target genes were identified by luciferase reporter assays. Our … Tīmeklis2024. gada 1. okt. · FEZF1-AS1 expression was significantly elevated in 34 CRC tissues compared with adjacent non-neoplastic mucosa tissues, and upregulated expression of FEZF1-AS1 was also identified in HCT116, M5 and LOVO cell lines. Moreover, high FEZF1-AS1 expression was associated with T-stage, lymph-node invasion and … banco santander empresarial internet banking